The Thyroid Scintigram

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Abstract
The hot nodule on the scintigram can be identified as autonomous or TSH (thyroid-stimulatin hormone)-dependent. The former represents a well defined pathophysiologic entity and can be correlated with a benign histologic picture. No case of a primary thyroid cancer fulfilling the criteria for the diagnosis of an autonomous hot nodule and masquerading as a benign lesion has been reported. It is a theoretical improbability. Papillary carcinomas have been reported within presumably autonomous nodules. These observations would seem to be of the same significance as the incidentical discovery of cancer in any other type of thyroid. The frequency of association of the hot autonomous nodule and thyroid cancer has not been determined.