Effect of Epinephrine on the Renal Circulation

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Abstract
The presence in malignant tumors of blood vessels which are atypical in appearance and at times extraordinarily profuse in number has been demonstrated frequently. Such “malignant” vessels have been studied in detail in brain tumors, but their presence in other areas, particularly in carcinomas of the kidney, has been thoroughly substantiated. Tumor vessels have also been noted on occasion in carcinoma of the stomach, pancreas, bladder, and liver. That these tumor vessels may carry an extraordinarily large amount of blood has frequently been demonstrated by serial angiography. That their pattern of arborization and their randomness of distribution need bear no similarity to that of normal vessels is apparent from accumulated roentgen data. It has been shown by microscopic and microangiographic studies that malignant tumors are supplied by both normal preformed vessels and by embryonic vessels, the walls of which are devoid of elastic tissue (3). There is suggestive evidence that these vessels are not resp...