Ecstasy and neurodegeneration
- 15 June 1996
- Vol. 312 (7045) , 1493-1494
- https://doi.org/10.1136/bmj.312.7045.1493
Abstract
Administration of ecstasy to various animals has been shown to cause long term destruction of serotoninergic axons and axon terminals in the brain. This damage occurs in rodents' brains and in several species of primate.2 Some reinnervation may occur …Keywords
This publication has 13 references indexed in Scilit:
- Walking on the moonThe Lancet, 1996
- The hyperthermic and neurotoxic effects of ‘Ecstasy’ (MDMA) and 3,4 methylenedioxyamphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor metabolizer phenotypeBritish Journal of Pharmacology, 1995
- The spin trap reagent α-phenyl-N-tert-butylnitrone prevents ‘ecstasy’-induced neurodegeneration of 5-hydroxytryptamine neuronesEuropean Journal of Pharmacology, 1995
- Review of the pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA or “Ecstasy”)Psychopharmacology, 1995
- Positron emission tomographic evidence for progression of human MPTP‐induced dopaminergic lesionsAnnals of Neurology, 1994
- Diversity of Psychopathology Associated with use of 3,4-Methylenedioxymethamphetamine (‘Ecstasy’)The British Journal of Psychiatry, 1994
- Serotonin Neurotoxicity after (±)3,4-Methylenedioxymethamphetamine (MDMA; “Ecstasy”): A Controlled Study in HumansNeuropsychopharmacology, 1994
- The demethylenation of methylenedioxymethamphetamine (“ecstasy”) by debrisoquine hydroxylase (CYP2D6)Biochemical Pharmacology, 1994
- (±3,4-Methylenedioxymethamphetamine Selectively Damages Central Serotonergic Neurons in Nonhuman PrimatesPublished by American Medical Association (AMA) ,1988
- Chronic Parkinsonism in Humans Due to a Product of Meperidine-Analog SynthesisScience, 1983