THE PROTEIN ANABOLIC ACTION OF MESTANOLONE

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Abstract
A controlled metabolic study of the steroid mestanolone was conducted on 20 females with chronic pulmonary tuberculosis, of whom 5 served as controls and 15 received 100 mg. of mestanolone daily. A statistically significant increase in weight occurred in the treated patients and was associated with a significant retention of nitrogen, potassium and phosphorus in the ratio in which they are normally found in protoplasm. The mean gain in body weight resulting from two courses of mestanolone (eighteen days each with an interval of eighteen days between) was 2.10 Kg., and the mean nitrogen retention was 1.89 Gm. daily.
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