Serum Protein, Enzyme and Immunoglobulin Responses Following Perineal Cryosurgery for Carcinoma of the Prostate

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Abstract
Alterations in serum proteins, enzymes and immunoglobulins were analyzed sequentially in 40 patients undergoing perineal cryosurgery for carcinoma of the prostate. A search was made for evidence of a tumor marker and for augmented host response attributable to an immune mechanisms. The data showed little evidence to support a systemic immune response. A reliable tumor marker could not be identified when cryosurgery was used alone.