Experimental Osteokeratoprosthesis

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Abstract
32 rabbits had penetrating keratoprostheses with autologous compact bone as a supporting flange. Previously transplanted fascia lata or preserved corium covered the bone graft to keep it in place. The bone, pretreated in various ways, was well tolerated and proved to be rather resistant to absorption and epithelial downgrowth. Optimal retention of the prosthesis occurred when it was secured by preplaced fascia lata. 18 out of 24 rabbits with fascia lata coverings had a fair result for as long as 8 months, whereas with corium 6 out of 8 were extruded. Various sizes of methyl-methacrylate rods, which simulated the optical system, permitted the study of the advantages and drawbacks of the different diameters and lengths of the anterior and posterior projection. The main complication was infection, which caused 4 corneal abscesses and panophthalmitis in 4 cases.

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