A modified synthesis of codamine under eschweiler‐clarke conditions
- 1 December 1968
- journal article
- research article
- Published by Wiley in Journal of Heterocyclic Chemistry
- Vol. 5 (6) , 753-755
- https://doi.org/10.1002/jhet.5570050603
Abstract
Codamine (1) was obtained in 88.4% yield by Eschweiler‐Clarke reaction of X with formalin and formic acid, whereas it formed in 46.2% yield in case of Mannich reaction of X with formalin and hydrochloric acid.Keywords
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