Inhibition of Macrophage Superoxide Production by Two Prenylated Flavanones fromErythrina sigmoidea Hua
- 1 August 1993
- journal article
- research article
- Published by Taylor & Francis in Natural Product Letters
- Vol. 3 (1) , 79-86
- https://doi.org/10.1080/10575639308043841
Abstract
Two prenylated flavanones namely sigmoidin A (SA) and sigmoidin B (SB) have been extracted from Erythrina sigmoidea Hua, a plant of Cameroon traditionally used in local medicine. An antioxidant activity was found and ascribed either to a direct reaction with O2 − or to a direct and/or indirect action on the membrane-bound enzyme NADPH oxidase. The formation of stable radicals was also demonstrated by electron spin resonance spectroscopy (ESR) and related to the antioxidant activity.Keywords
This publication has 13 references indexed in Scilit:
- Generation of free radicals by simple prenylated hydroquinone derivatives, natural antitumor agents from the marine urochordate Aplidium californicumChemical Research in Toxicology, 1991
- Antioxidant properties of natural hydroquinones from the marine colonial tunicate aplidium californicumFree Radical Biology & Medicine, 1991
- Flavonoids as superoxide scavengers and antioxidantsFree Radical Biology & Medicine, 1990
- Antimicrobial Activity of two Flavanones Isolated from the Cameroonian PlantErythrina sigmoideaPlanta Medica, 1988
- Radical Scavenging by Flavonoid AntioxidantsFree Radical Research Communications, 1987
- Erythrina studies. Part 2. Structures of three novel prenylated antibacterial flavanones, sigmoidins A–C, from Erythrina sigmoidea HuaJournal of the Chemical Society, Perkin Transactions 1, 1986
- Simulation of isotropic electron spin resonance spectra: a transportable basic programCanadian Journal of Chemistry, 1982
- Electron paramagnetic resonance spectra of flavonoid anion-radicalsJournal of the Chemical Society B: Physical Organic, 1969
- Electron spin resonance studies of the semiquinone radical anions of 1,2,4-trihydroxybenzene and its methyl derivativesJournal of the Chemical Society B: Physical Organic, 1969
- Electron spin resonance in tert-butyl-substituted semiquinones. The hyperfine structure of tert-butyl protonsJournal of the American Chemical Society, 1968