47,XXY Klinefelter's Syndrome with Low FSH and LH Levels and Absence of Leydig Cells
- 24 April 2009
- journal article
- research article
- Published by Hindawi Limited in Andrologia
- Vol. 12 (5) , 426-433
- https://doi.org/10.1111/j.1439-0272.1980.tb01693.x
Abstract
Examination of testicular biopsy from a patient with 47,XXY Klinefelter''s syndrome revealed a diffuse hyalinization of seminiferous tubules as well as an absence of mature Leydig cells. Ultrastructural findings showed some immature Leydig cells in the testicular interstitium. Hormone assays revealed low serum FSH [follitropin] and LH [lutropin] levels. The association of both, hormone assays and testicular morphologic pattern, suggests the presence of a Klinefelter''s syndrome with hypogonadotropic hypogonadism.Keywords
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