Abstract
In 15 expts. on 13 normal adult [male] cats, the plasma vol. was detd. by the blue dye T-1824. Following a control period averaging 100 mins., ether anesthesia was induced. Changes in plasma vol. during a 30-75 min. period of anesthesia were estimated from alterations in the serum cone, of the dye, and from changes in serum protein cone. In 5 expts., hematocrit detns. were also made. In normal cats, ether does not cause a reduction in plasma vol. There was no significant change in dye cone, curve, serum protein, or hematocrit values during the period of anesthesia.