A T‐Cell Marker in Mouse Fibroblast × T‐Lymphocyte Somatic Cell Hybrids

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Abstract
Continuous hybrid cell lines were generated by the fusion of allogeneically primed murine T [thymus derived] lymphocytes with mouse L cell-derived fibroblasts of line 613. The resulting hybrid clones express 1 or more T-cell-specific surface components identifiable by radioiodination of intact cells followed by NP-40 solubilization of membrane proteins and sodium dodecyl sulfate polyacrylamide gel electrophoresis. These markers are stably expressed by the hybrid lines after several months of passage.