Stereo- and Regiocontrolled Construction of Trisubstituted Piperidines Using a TpMo(CO)2(Dihydropyridine) Scaffold (Tp = Hydridotrispyrazolylborate)
- 3 October 2000
- journal article
- research article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 65 (22) , 7445-7455
- https://doi.org/10.1021/jo0007128
Abstract
Cationic TpMo(CO)2(dihydropyridine) complexes (Tp = hydridotrispyrazolylborate), readily generated from 3-oxo-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester, represent scaffolds from which (by judicious choice of demetalation conditions) either 2,3,6- or 2,5,6-trisubstituted-1,2,3,6-tetrahydropyridines can be prepared in a regio- and stereodefined way.Keywords
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