A Review of the Microbiology of Amoxycillin/Clavulanic Acid Over the 15 Year Period 1978-1993
- 1 October 1994
- journal article
- review article
- Published by Taylor & Francis in Journal of Chemotherapy
- Vol. 6 (5) , 283-318
- https://doi.org/10.1080/1120009x.1994.11741165
Abstract
A review of the published literature over the period 1978-1993 was undertaken to assess any changes in the prevalence of β-lactamase-producing bacterial pathogens and also any changes in the susceptibility in these pathogens to amoxycillin/clavulanate. The review has involved the examination of over 1500 publications. The review shows that in general there has been an increase in the frequency of β-lactamaseproducing pathogens resistant to ampicillin and amoxycillin but there is no evidence for any significant increase in resistance to amoxycillin/clavulanate over the period of the review.Keywords
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