SELECTIVE LOSS OF BLOOD GROUP ANTIGENS DURING WOUND HEALING
- 15 August 2009
- journal article
- research article
- Published by Wiley in Acta Pathologica Microbiologica Scandinavica Section A Pathology
- Vol. 84A (6) , 445-450
- https://doi.org/10.1111/j.1699-0463.1976.tb00141.x
Abstract
Frozen sections of healing wounds of the oral mucosa of 3 rhesus monkeys were examined by a double layer immunofluorescent technique for the presence of blood group B-like antigens. Antigen activity was present in normal epithelium and in the epithelial outgrowth into the wounds, but was absent from the outgrowth following treatment with lipid solvents. Thus glycoprotein, but not glycolipid associated antigen, is probably lost from the surface of epithelial cells during wound healing, a pattern of selective loss which may reflect a difference between regenerative and neoplastic lesions.Keywords
This publication has 23 references indexed in Scilit:
- QUANTITATIVE DETERMINATION OF BLOOD GROUP SUBSTANCES A OF ORAL EPITHELIAL CELLS BY IMMUNOFLUORESCENCE AND IMMUNOPEROXIDASE METHODSActa Pathologica Microbiologica Scandinavica Section A Pathology, 2009
- A SENSITIVE IMMUNOFLUORESCENCE TECHNIQUE FOR DETECTING BLOOD GROUP SUBSTANCES A AND BActa Pathologica Microbiologica Scandinavica Section A Pathology, 2009
- LOSS OF EPITHELIAL BLOOD GROUP ANTIGENS A AND B IN ORAL PREMALIGNANT LESIONSActa Pathologica Microbiologica Scandinavica Section A Pathology, 1975
- Organization of glycolipids and glycoproteins in surface membranes: Dependency on cell cycle and on transformationBiochemical and Biophysical Research Communications, 1974
- LOSS OF EPITHELIAL BLOOD GROUP ANTIGEN‐A DURING WOUND HEALING IN ORAL MUCOUS MEMBRANEActa Pathologica Microbiologica Scandinavica Section A Pathology, 1974
- Independent behaviour of blood group A- and B-like activities in gastric carcinomata of blood group AB individualsNature, 1974
- LOSS OF EPITHELIAL BLOOD GROUP SUBSTANCE A IN ORAL CARCINOMASActa Pathologica Microbiologica Scandinavica Section A Pathology, 1973
- Early Immunologic Diagnosis and Prognosis of Carcinoma:Philip Levine Award AddressAmerican Journal of Clinical Pathology, 1972
- A, B and H Blood Group Specificities in Glycoprotein and Glycolipid Fractions of Human Erythrocyte Membrane. Absence of Blood Group Active Glycoproteins in the Membranes of Non‐SecretorsVox Sanguinis, 1971
- THE DISTRIBUTION OF BLOOD-GROUP SUBSTANCES IN HUMAN GASTRIC AND DUODENAL MUCOSAThe Lancet, 1957