Sequential analysis by cooperative reactions on copolymers. II. Binary copolymers with one protecting monomer type

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Abstract
We develop an exact theory for the kinetics of reactions on linear binary copolymers. One of the two types of monomer units is assumed to exhibit a cooperative effect in the sense that after such a unit has reacted, the reactivities of the adjacent two monomer units are changed. Hence the reaction pattern depends upon the sequential structure of the copolymer. Both periodic and aperiodic copolymers are considered: in particular, random, Markovian, and second‐order Markovian sequential structures.