EVIDENCE FOR A CONTRIBUTION OF THE AUDITORY CORTEX TO AUDIOSPINAL FACILITATION IN MAN

Abstract
Facilitation of the spinal monosynaptic reflex by auditory stimulation has been demonstrated previously in animals and man. Analysis of the time course of audiospinal facilitation (ASF) in normal subjects is reported. The role of the cerebral cortex in the control of audiospinal facilitation was investigated in 32 patients with anatomically well-circumscribed lesions, the precise topography of which was determined stereotaxically. Lesions of the caudal part (Heschl's gyrus and temporal plane) of the superior temporal gyrus selectively depressed ASF evoked by contralateral auditory stimulation. In contrast, lesions in temporal, parietal and occipital lobes had no effect. Results obtained with frontal lobe lesions were not homogeneous. The specific involvement of auditory cortex in the gating of behavioural audiomotor reactions is discussed.