Dual inhibition of topoisomerase II and tubulin polymerization by azatoxin, a novel cytotoxic agent
- 1 June 1993
- journal article
- research article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 45 (12) , 2449-2456
- https://doi.org/10.1016/0006-2952(93)90226-m
Abstract
No abstract availableKeywords
This publication has 15 references indexed in Scilit:
- Synthesis of alkoxy-substituted diaryl compounds and correlation of ring separation with inhibition of tubulin polymerization: differential enhancement of inhibitory effects under suboptimal polymerization reaction conditionsJournal of Medicinal Chemistry, 1992
- Feasibility of a High-Flux Anticancer Drug Screen Using a Diverse Panel of Cultured Human Tumor Cell LinesJNCI Journal of the National Cancer Institute, 1991
- Display and Analysis of Patterns of Differential Activity of Drugs Against Human Tumor Cell Lines: Development of Mean Graph and COMPARE AlgorithmJNCI Journal of the National Cancer Institute, 1989
- DNA TOPOISOMERASE POISONS AS ANTITUMOR DRUGSAnnual Review of Biochemistry, 1989
- Synthesis and antitumor activity of podophyllotoxin aza-analoguesTetrahedron Letters, 1989
- Differential effects of magnesium on tubulin-nucleotide interactionsBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1985
- Adriamycin-Induced DNA Damage Mediated by Mammalian DNA Topoisomerase IIScience, 1984
- Separation of active tubulin and microtubule-associated proteins by ultracentrifugation and isolation of a component causing the formation of microtubule bundlesBiochemistry, 1984
- Formation and rejoining of deoxyribonucleic acid double-strand breaks induced in isolated cell nuclei by antineoplastic intercalating agentsBiochemistry, 1984
- Protein-associated deoxyribonucleic acid strand breaks in L1210 cells treated with the deoxyribonucleic acid intercalating agents 4'-(9-acridinylamino)methanesulfon-m-anisidide and adriamycinBiochemistry, 1981