The HLA system in the prevalent Mexican Indian group: the Nahuas

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Abstract
Results of HLA-A, B and C typing as well as haplotype frequencies in the Nahuas, who are the predominant Indian group in Mexico, are presented. ABO and Rh blood groups show the genetic homogeneity of this population, since all were group O and Rh+. The most frequent antigens and haplotype are in general the same as in some, but not all Amerindian tribes (Papago, Pimas, Zuni from North America and Ixils from Guatemala). When compared to other Mongoloids, the HLA pattern is very close to the Japanese population. Antigens Bw39 and Cw4 look like markers of Nahuas. Because Bw16 cells from 4 individuals could not be assigned either as Bw38 or Bw39 and 6 subjects did not type for any of the Bw22 splits, new subtypes of these antigens are probable.