17β-Estradiol: Inducer of Uterine Hexokinase
- 1 March 1968
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 159 (3818) , 990-991
- https://doi.org/10.1126/science.159.3818.990
Abstract
Administration of estradiol to ovariectomized rats induced new synthesis of uterine hexokinase which was prevented by actinomycin D, 5-fluorouracil, cycloheximide, or ethionine. The estradiol-induced increase in uterine hexokinase activity was detectable as early as 4 hours. The increase in enzyme activity was dependent upon the dose of the hormone. The evidence indicates that the increased hexokinase activity induced by 17β-estradiol may entail an acceleration of the synthesis of certain RNA species.This publication has 18 references indexed in Scilit:
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