THE ROLE OF PROTEIN SYNTHESIS IN EARLY ESTROGEN ACTION
- 1 February 1961
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 47 (2) , 164-169
- https://doi.org/10.1073/pnas.47.2.164
Abstract
The administration of puromycin to ovariectomized rats blocked uterine protein synthesis in vivo without inhibition of phos-pholipid or ribonucleic acid synthesis. Under the same conditions, puromycin treatment also prohibited the early acceleration of phos-pholipid and ribonucleic acid synthesis by estradiol and prevented the hormone-induced imbibition of water in the uterus. The essentiality of protein synthesis for early estrogen action is discussed.This publication has 13 references indexed in Scilit:
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