SUPPRESSED LYMPHOCYTE BLASTOGENIC RESPONSES AND ENHANCED INVITRO GROWTH OF INFECTIOUS BOVINE-RHINOTRACHEITIS VIRUS IN STRESSED FEEDER CALVES
- 1 January 1983
- journal article
- research article
- Vol. 44 (11) , 2145-2148
Abstract
Hereford steers were stressed on a large-animal treadmill operating at speeds of 1.8 to 2.2 m/s. Blood samples were collected from indwelling jugular catheters before, during and after exercise. Peripheral blood lymphocytes from stressed calves at 5 and 30 min after exercise had less (P < 0.01) mitogen-induced blastogenic responses when compared to pre- or 60-min postexercise values. Serum from stressed calves incorporated into lymphocyte cultures from nonstressed steers resulted in less (P < 0.01) lymphocyte blastogenic responses. Infectious bovine rhinotracheitis viral growth in bovine kidney cell cultures was enhanced 4-fold when cultured with serum from stressed calves. These data indicate that acute physical exertion may cause physiologic alterations in calves that modulate cellular immunity and viral replication.This publication has 22 references indexed in Scilit:
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