Use of mefenamic acid in the treatment of primary dysmenorrhea
- 22 June 1979
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 241 (25) , 2713-2716
- https://doi.org/10.1001/jama.241.25.2713
Abstract
Mefenamic acid (Ponstel [a prostaglandin synthesis inhibitor]), 250 mg 4 .times. a day, and placebo were compared in a double-blind, crossover study conducted in 46 women with primary spasmodic dysmenorrhea. When compared with placebo, treatment with mefenamic acid resulted in significant decreases in the frequency and severity of the symptoms, and significantly reduced the need for additional analgesic medication. Mefenamic acid was well tolerated. No changes in clinical laboratory values were associated with its use.This publication has 3 references indexed in Scilit:
- TRIAL OF PROSTAGLANDIN-SYNTHETASE INHIBITORS IN PRIMARY DYSMENORRHŒAThe Lancet, 1978
- Mefenamic Acid in DysmenorrheaActa Obstetricia et Gynecologica Scandinavica, 1977
- Inhibition of prostaglandin F2α-induced reflex bradycardia and hypotension by meclofenamic acidProstaglandins, 1976