The impact of spacer structure on 5-HT7 and 5-HT1A receptor affinity in the group of long-chain arylpiperazine ligands
- 1 December 2004
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 14 (23) , 5863-5866
- https://doi.org/10.1016/j.bmcl.2004.09.029
Abstract
No abstract availableKeywords
This publication has 18 references indexed in Scilit:
- Serotonin7 Receptors (5-HT7Rs)and their LigandsCurrent Medicinal Chemistry, 2004
- 5-HT7 ReceptorsCurrent Drug Targets-CNS & Neurological Disorders, 2004
- Optimization of the Pharmacophore Model for 5-HT7R Antagonism. Design and Synthesis of New Naphtholactam and Naphthosultam DerivativesJournal of Medicinal Chemistry, 2003
- Synthesis and Structure−Affinity Relationships of 1-[ω-(4-Aryl-1-piperazinyl)alkyl]-1-aryl Ketones as 5-HT7Receptor LigandsJournal of Medicinal Chemistry, 2003
- SB-656104-A: A novel 5-HT7 receptor antagonist with improved In vivo propertiesBioorganic & Medicinal Chemistry Letters, 2002
- High-affinity interactions of ligands at recombinant Guinea pig 5HT7 receptorsJournal of Computer-Aided Molecular Design, 2001
- A Novel, Potent, and Selective 5-HT7Antagonist: (R)-3-(2-(2-(4-Methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl)phenol (SB-269970)Journal of Medicinal Chemistry, 2000
- Cloning and Expression of a 5‐Hydroxytryptamine7 Receptor Positively Coupled to Adenylyl CyclaseJournal of Neurochemistry, 1994
- A novel adenylyl cyclase-activating serotonin receptor (5-HT7) implicated in the regulation of mammalian circadian rhythmsNeuron, 1993
- NAN-190: an arylpiperazine analog that antagonizes the stimulus effects of the 5-HT1A agonist 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT)European Journal of Pharmacology, 1988