Phase I/II Trial of Capecitabine, Oxaliplatin, and Radiation for Rectal Cancer
- 15 August 2003
- journal article
- clinical trial
- Published by American Society of Clinical Oncology (ASCO) in Journal of Clinical Oncology
- Vol. 21 (16) , 3098-3104
- https://doi.org/10.1200/jco.2003.02.505
Abstract
Purpose: The purpose of this study was to establish the feasibility and efficacy of preoperative radiotherapy (RT) with concurrent capecitabine and oxaliplatin (XELOX-RT) in patients with rectal cancer.Keywords
This publication has 18 references indexed in Scilit:
- Phase I Trial Evaluating the Concurrent Combination of Radiotherapy and Capecitabine in Rectal CancerJournal of Clinical Oncology, 2002
- Radiosensitization by oxaliplatin in a mouse adenocarcinoma: influence of treatment scheduleInternational Journal of Radiation Oncology*Biology*Physics, 2002
- Trimetrexate as biochemical modulator of 5-fluorouracil/leucovorin in advanced colorectal cancer: final results of a randomised European studyAnnals of Oncology, 2002
- Adjuvant versus Neoadjuvant Radiochemotherapy for Locally Advanced Rectal Cancer A Progress Report of a Phase-III Randomized Trial (Protocol CAO/ARO/AIO-94)Strahlentherapie und Onkologie, 2001
- Leucovorin and Fluorouracil With or Without Oxaliplatin as First-Line Treatment in Advanced Colorectal CancerJournal of Clinical Oncology, 2000
- Preferential activation of capecitabine in tumor following oral administration to colorectal cancer patientsCancer Chemotherapy and Pharmacology, 2000
- Phase III Multicenter Randomized Trial of Oxaliplatin Added to Chronomodulated Fluorouracil–Leucovorin as First-Line Treatment of Metastatic Colorectal CancerJournal of Clinical Oncology, 2000
- Long-term survival of patients with unresectable colorectal cancer liver metastases following infusional chemotherapy with 5-fluorouracil, leucovorin, oxaliplatin and surgeryAnnals of Oncology, 1999
- Improving Adjuvant Therapy for Rectal Cancer by Combining Protracted-Infusion Fluorouracil with Radiation Therapy after Curative SurgeryNew England Journal of Medicine, 1994
- Radiation therapy and fluorouracil with or without semustine for the treatment of patients with surgical adjuvant adenocarcinoma of the rectum. Gastrointestinal Tumor Study Group.Journal of Clinical Oncology, 1992