Follow‐up plans after treatment of primary colon and rectum cancer
- 1 September 1991
- journal article
- review article
- Published by Wiley in World Journal of Surgery
- Vol. 15 (5) , 583-588
- https://doi.org/10.1007/bf01789202
Abstract
Although some would argue about the value of routine follow-up of patients with colon and rectal cancer, well designed programs of testing have been shown to identify treatable recurrence at its earliest detectable stage. Treatment of these recurrences appears to be associated with improved survival. Newer applications of radiolabeled antibodies that are directed to specific or nonspecific cell surface epitopes may increase the value of serologic tumor markers. Ultimately, the application of progressively more stringent cost controls in our medical care delivery systems will demand that follow-up tests be proven of value either in a curative or palliative sense to the patient with recurrent disease. Bien que discutée par certains, la surveillance systématique du côlon des patients, combinée avec quelques tests simples permet de détecter des récidives des cancers colo-rectaux à un stade précoce, avec, semble-t'il, une amélioration de survie. Actuellement, l'utilisation d'anticorps marqués, qui se dirigent contre les épitopes cellulaires de surface, spécifiques ou non, peut éventuellement améliorer la rentabilité des marqueurs tumoraux sériques classiques. Ultérieurement, devant l'application de plus en plus répandue de programmes d'évaluation des soins et de coût/efficacité, il faudrait apprécier la valeur exacte de ces tests dans le traitement, à visée curative ou palliative, de ces récidives. Aunque algunos podrían argumentar en favor del simple seguimiento rutinario de pacientes con cáncer de colon y recto, se ha demostrado que programas bien diseñados de pruebas especiales de seguimiento son capaces de identificar recurrencias susceptibles de tratamiento en las etapas más tempranas de detección. Las nuevas aplicaciones de anticuerpos radiomarcados dirigidos contra epitopes de superficie celular, específicos o no específicos, pueden incrementar el valor de los marcadores séricos tumorales. Por último, la aplicación de controles de costo, crecientemente estrictos en nuestros sistemas de atención de la salud, exige que las pruebas y examenes de seguimiento deben ser de probado valor en cuanto a la curación o paliación del paciente con enfermedad recurrente.Keywords
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