On the binding of iabelled saxitoxin to the squid giant axon
- 22 August 1984
- journal article
- Published by The Royal Society in Proceedings of the Royal Society of London. B. Biological Sciences
- Vol. 222 (1227) , 147-153
- https://doi.org/10.1098/rspb.1984.0055
Abstract
Measurement of the maximum saturable binding capacity for 3H-labelled saxitoxin in well cleaned giant axons from Loligo forbesi gave a value of 290 +/- 65 (s.e.m.) binding sites per square micrometre of membrane. In samples of the fin nerve the total saturable uptake was 12.4 +/- 2.4 fmol mg-1 wet mass, corresponding to 94 sites per square micrometre for fibres whose mean diameter after fixation and embedding was estimated as 16 micron.Keywords
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