New anthracyclinone metabolites from two blocked mutants of Streptomyces galilaeus MA144-M1.
- 1 January 1982
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 35 (12) , 1641-1645
- https://doi.org/10.7164/antibiotics.35.1641
Abstract
Two blocked mutants of the aclacinomycin-producing S. galilaeus MA144-M1 produced new anthraquinones and anthracyclinones. The mutant ANR-58 produced compounds 58A, 58B, 58C (7-deoxy-2-hydroxyaklavinone), 58D (2-hydroxyaklavinone) and 58WR. All these compounds have the 2-hydroxyl group. The mutant ANR-665 produced compounds 665A and 665B. The compounds 58A, 58B and 665A have an anthraquinone skeleton.This publication has 2 references indexed in Scilit:
- New anthracycline metabolites from mutant strains of Streptomyces galilaeus MA144-M1. II. Structure of 2-hydroxyaklavinone and new aklavinone glycosides.The Journal of Antibiotics, 1981
- New anthracycline metabolites from mutant strains of Streptomyces galilaeus MA144-M1. I. Isolation and characterization of various blocked mutants.The Journal of Antibiotics, 1981