Small-Airways Dysfunction in Passive Smokers

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To the Editor: White and Froeb state in the March 27 issue that they found differences in mid-expiratory and end-expiratory flow (FEF 25–75% and FEF 75–85%) in their comparison of nonsmokers with passive smokers and smokers. This statement is remarkable since not all investigators who have used FEF 25–75% have been able to distinguish between smokers and nonsmokers, 1 , 2 because only a limited number of smokers had abnormal test results.3 The dose–response relation found by Cuddeback et al., 4 indicated that the values for FEF 25–75% and FEF 75–85% were decreased in passive smokers by 13 per cent and 25 per cent, . . .