Statins and the Risk of Colorectal Cancer
Top Cited Papers
Open Access
- 26 May 2005
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 352 (21) , 2184-2192
- https://doi.org/10.1056/nejmoa043792
Abstract
Statins are inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase and effective lipid-lowering agents. Statins inhibit the growth of colon-cancer cell lines, and secondary analyses of some, but not all, clinical trials suggest that they reduce the risk of colorectal cancer.Keywords
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