LYMPHOCYTE-ASSOCIATED IMMUNE-RESPONSES TO CANINE-DISTEMPER AND MEASLES VIRUSES IN DISTEMPER-INFECTED GNOTOBIOTIC DOGS
- 1 January 1979
- journal article
- research article
- Vol. 40 (5) , 669-672
Abstract
Cellular immune responses or peripheral blood lymphocytes to canine distemper virus and measles virus were determined in vaccinated or infected gnotobiotic dogs using the syncytia inhibition technique. Cross-reactivity between viruses was detected in both groups of dogs. Peak responses in vaccinated dogs occurred 11 days after vaccination and declined to base-line levels by 3 wk, whereas responses in infected dogs were present 30 days after inoculation. Fractionation experiments with peripheral blood lymphocytes indicated that syncytia inhibition was probably mediated by T [thymus-derived] lymphocytes.This publication has 10 references indexed in Scilit:
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