Sequence‐specific [1H]NMR resonance assignments and secondary structure identification for 1‐ and 2‐zinc finger constructs from SWI5

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Abstract
Complete [1H]NMR resonance assignments are presented for the second of the three zinc fingers from SWI5 as it appears in both 1‐ and 2‐finger constructs. Signals from finger 2 are unaffected by the presence or absence of finger 1, showing that the protein has a modular construction. The structure of finger 2 comprises a helix running from N56 to Q67, and a region approximating to an anti‐parallel β‐sheet running from Y42 to F53. These features combine to produce a hydrophobic core in the structure involving the invariant residues Y42, F53, L59 and H62.