Abstract
In glucose broth cultures of a strain of S. pyogenes more O2 was consumed per mole of glucose used and less lactic acid formed while the cultures were alkaline than after they became acidic. Whether this is a true pH effect or one of cell aging was not apparent from the data obtained. Resting cells oxidized galactose more completely than glucose and converted less of it to lactic acid. A possible explanation for the quantitative differences in the dissimilation of the 2 sugars by resting cells is presented, based on rates of sugar utilization and on experiments involving pyruvic acid as substrate.