The Preparation and Evaluation of Some Phenolic Ethers as Antifungal Agents
- 1 December 1959
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 11 (Supplement) , 240T-249T
- https://doi.org/10.1111/j.2042-7158.1959.tb10439.x
Abstract
A series of phenolic ethers, derivatives of hydroxybenzoic acids, benzaldehydes and acylophenones have been prepared and tested in vitro for antifungal action. The highest activity was found in those compounds having an amyloxy group ortho to a carbonyl radical. Data are presented on the in vivo antifungal activity and toxicity of 2-n-amyloxybenzamide and 2-n-amyloxyacetophenone.Keywords
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