HEART SIZE IN SHOCK PRODUCED BY VENOUS OCCLUSION OF THE HIND LIMBS OF THE DOG

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Abstract
Changes in heart size following the production of shock by bilateral venous occlusion of the hind limbs of the dog were studied by means of x-ray. X-ray films of the heart in the anteroposterior and left lateral positions were taken, retraced, and the shadow area detd. by planimetry. In some expts., heart rate was controlled by atropinization. Control studies showed that a change of heart size of 5%, if uniform and consistent, was significant, and a 10% change was unequivocal. The operative procedure employed led to a consistent decline in heart size greatest in the 1st hr. This decline was attributed to the loss of circulating blood vol. as shock developed, the rate of loss lessening as the expt. progressed. The rate of decline in heart size lessened after the first quarter of the post-operative survival and later the heart size did not change or, even, increased slightly. It is suggested that these later changes may be due, in part at least, to the development of myocardial ischemia, as a result of the slowed rate of blood flow, shared by the coronary circuit, leading to a loss of cardiac tone.

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