Renal Threshold for Ascorbic Acid in Twelve Normal Adults

Abstract
Renal threshold values for ascorbic acid for twelve normal adults, four men and eight women, ranged from 1.1 to 1.8 mg. per cent. Values for ten of the twelve subjects were within a range of 1.1 to 1.3 mg. per cent. Of six subjects receiving 74 mg. of ascorbic acid daily for from 12 to 14 days, three maintained tissue saturation if the excretion of half of the test dose in 24 hours is used as a criterion, whereas three gave evidence of slight depletion of tissue reserves of ascorbic acid on this intake.