Morphological Study of Autologous Rosettes (A‐RFC)
- 1 January 1979
- journal article
- research article
- Published by Wiley in Scandinavian Journal of Immunology
- Vol. 9 (1) , 15-21
- https://doi.org/10.1111/j.1365-3083.1979.tb02701.x
Abstract
The morphology of A-RFC was studied by light and EM. A-RFC were obtained from the spleen of adult thymectomized (ATx) or nude mice, and from neonatal thymus grafts during the regeneration phase. Among the auto-rosettes seen by light microscopy, 76% of them were formed by lymphoid cells which included a high proportion of large lymphocytes (48%). EM study performed after isolation of A-RFC by micromanipulation demonstrated that 74% were formed by large lymphoid cells with an immature nucleus. The finding of such large-sized lymphoid cells with immature nuclei indicates that A-RFC might belong to an immature T [thymus-derived] cell class.This publication has 19 references indexed in Scilit:
- Ultrastructural study of spontaneous bone marrow rosette-forming cells.The Journal of cell biology, 1977
- Adult thymectomy promotes the manifestation of autoreactive lymphocytesCellular Immunology, 1977
- Morphological definition of thymocyte subpopulationsCell and tissue research, 1975
- Five types of lymphocytes (lg− θ−, lg− θ+ weak, lg− θ+strong, lg+ θ− and lg+ θ+) characterized by double immunofluorescence and electrophoretic mobility Organ distribution in normal and nude miceEuropean Journal of Immunology, 1975
- HUMORAL THYMIC FACTORS INFLUENCING POSTTHYMIC CELLS*Annals of the New York Academy of Sciences, 1975
- Antigen recognition by T lymphocytes: IV. Differences in antigen-binding characteristics of T- and B-RFC: A cause for variations in the evaluation of T-RFCCellular Immunology, 1973
- IN-VITRO DEMONSTRATION OF THYMIC HORMONE IN THE MOUSE BY CONVERSION OF PRECURSOR CELLS INTO LYMPHOCYTESThe Lancet, 1973
- A SCANNING AND TRANSMISSION ELECTRON MICROSCOPE STUDY OF ANTIGEN-BINDING SITES ON ROSETTE-FORMING CELLSThe Journal of Experimental Medicine, 1973
- Rosette-forming cells in the unimmunized mouse: Morphological studies with phase contrast and electron microscopyCellular Immunology, 1971
- REGENERATION OF THYMUS GRAFTS. I. HISTOLOGICAL AND CYTOLOGICAL ASPECTSTransplantation, 1965