Studies of Staphylococci with Special Reference to the Coagulase-positive Types

Publisher Website
Google Scholar
Abstract
A physiological and nutritional study of 19 coagulase-positive and 66 coagulase-negative staphylococci indicated that the staphylococci that give a positive coagulase reaction comprise a rather homogenous group. They ferment mannitol, tend to produce pigment, generally give a positive Stone reaction, ferment glucose, lactose, sucrose, and glycerol, and require added thiamine and nicotinic acid. They may be separated from the coagulase-negative strains by the ability of the coagulase-positive strains to ferment mannitol under anaerobic conditions and to grow in a synthetic medium devoid of biotin. Among the coagulase-negative staphylococci, 6 strains were found to require pantothenic acid and 2 required pyridoxine. These requirements appear to be unique among the staphylococci thus far reported.