Selenium-independent glutathione peroxidase activity in rabbit liver
- 30 September 1980
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Biochemistry
- Vol. 58 (10) , 1012-1017
- https://doi.org/10.1139/o80-137
Abstract
The reduction of linoleic acid hydroperoxide catalyzed by rat liver cytosol is catalyzed by a Se-dependent glutathione peroxidase. The activity in rabbit liver cytosol could also be attributed to a Se-independent glutathione peroxidase present in an amount approximately equal to the Se-dependent peroxidase. The Se-independent peroxidase copurified with glutathione transferase B and was completely inhibited by antitransferase B antiserum and transferase substrates. Glutathione transferase B in rabbit liver cytosol is involved in the intracellular decomposition of lipid peroxide and could explain the lower Se requirement of rabbits in comparison with other species.This publication has 18 references indexed in Scilit:
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