THE ADRENAL CORTEX AND THE LYMPHOCYTOPENIA DUE TO GLUCOSE ADMINISTRATION

Abstract
LYMPHATIC atrophy and lymphopenia are common symptoms of the alarm reaction (Harlow and Selye 1937, Elmadjian and Pincus 1945). The pronounced activity of the 11-oxygenated corticosteroids in inducing lymphatic regression and lymphopenia (Dougherty and White 1944) has led to the concept that the adrenal cortex through its secretions is a primary regulator of these phenomena (Selye 1946). We have, in fact, employed the lymphocyte count as an indicator of adrenocortical function in normal and psychotic subjects, especially in relation to acutely stressful situations (Hoagland, Elmadjian and Pincus 1946, Pincus and Elmadjian 1946, Pincus 1946).

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