Mice coisogenically immunized against H-2 class I antigens on transfected l cells reject transplanted embryonal carcinoma cells
- 1 December 1985
- journal article
- research article
- Published by Springer Nature in Immunogenetics
- Vol. 22 (6) , 533-541
- https://doi.org/10.1007/bf00430301
Abstract
Evidence is presented of the ability of H-2 class I antigens to function as teratocarcinoma transplantation (Gt) antigens. Coisogenic immunization against H-2 class I antigens expressed on transfected L cells is shown to induce resistance to embryonic carcinoma (EC) cell allografts. The Kb, Db, Dd, and, in appropriate recipients, Ld antigens can function as Gt antigens. The protocol presented may be useful for the molecular identification of other genes encoding histocompatibility antigens.This publication has 33 references indexed in Scilit:
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