Chronic Cigarette Smoking
- 17 July 1972
- journal article
- research article
- Published by American Medical Association (AMA)
- Vol. 221 (3) , 282-285
- https://doi.org/10.1001/jama.1972.03200160034010
Abstract
The effect of chronic cigarette smoking upon adrenocortical and sympathoadrenomedullary activity was studied in 94 normal males. Plasma cortisol levels at 8 AM and 4 PM obtained in six habitual smokers of one to two packs per day and in six nonsmokers were comparable and showed a normal circadian variation. Twenty-four hour urinary 17-hydroxycorticosteroid, 11-hydroxycorticosteroid, cortisol, and catecholamine excretion were assayed in 25 habitual smokers of one-half to one pack per day, 23 smokers of one to two packs per day, and in 34 nonsmokers. No significant differences were noted. Ordinary cigarette smoking does not appear to interfere with clinical assessment of pituitary-adrenocortical and sympathoadrenomedullary activity. Also, these data fail to implicate overactivity of these systems in the pathogenesis of cardiovascular and other disorders found in the habitual cigarette smoker of less than two packs per day.Keywords
This publication has 5 references indexed in Scilit:
- Action of Nicotine and Tobacco-Smoking on the Adrenal MedullaArchives of internal medicine (1960), 1961
- Effect of Smoking on the Fasting Blood Sugar and Pressor AminesCirculation, 1959
- Effect of Smoking on the Urinary Output of Epinephrine and Norepinephrine in ManJournal of Applied Physiology, 1956
- Pharmacology of Nicotine: Antipyretic, Renal and Adrenocorticotrophic Effects.Experimental Biology and Medicine, 1951
- THE PITUITARY‐ADRENAL SYSTEMAnnals of the New York Academy of Sciences, 1949