Rate studies of unsaturated fatty acid oxidation catalyzed by hematin compounds

Abstract
Summary: Hemoglobin and hematin were found to catalyze the oxidation of homogeneous as well as heterogeneous linoleate systems. The interrelationship of several factors affecting the rates of this reaction were studied.A spectrophotometric method was developed for studying the rate of decomposition of linoleate hydroperoxide by hematin compounds. By using this method, the effects of linoleate hydroperoxide, hemoglobin concentrations, and temperature on the rate of hydroperoxide decomposition was studied. In addition, the catalytic activities of several hemoproteins, metallo‐protoporphyrins, and metal chelate compounds were determined.