Localization of Drug‐Metabolizing Enzyme Activities to Blood‐Brain Interfaces and Circumventricular Organs
- 1 March 1994
- journal article
- research article
- Published by Wiley in Journal of Neurochemistry
- Vol. 62 (3) , 1089-1096
- https://doi.org/10.1046/j.1471-4159.1994.62031089.x
Abstract
The brain, with the exception of the choroid plexuses and Circumventricular organs, is partially protected from the invasion of blood-borne chemicals by the specific morphological properti...Keywords
This publication has 42 references indexed in Scilit:
- Brain Synthesis and Cerebrovascular Action of Epoxygenase Metabolites of Arachidonic AcidJournal of Neurochemistry, 1992
- Blood–Brain Barrier Pericytes Are the Main Source of γ‐Glutamyltranspeptidase Activity in Brain CapillariesJournal of Neurochemistry, 1992
- Drug metabolizing enzymes in the brain and cerebral microvesselsBrain Research Reviews, 1991
- NADPH:cytochrome P-450(c) reductase: Biochemical characterization in rat brain and cultured neurons and evolution of activity during developmentNeurochemical Research, 1989
- A new aspect of the protective functions of the blood-brain barrier: Activities of four drug-metabolizing enzymes in isolated rat brain microvesselsLife Sciences, 1988
- Evidence for an Alanine, Serine, and Cysteine System of Transport in Isolated Brain CapillariesJournal of Cerebral Blood Flow & Metabolism, 1987
- The activity of 1-naphthol-UDP-glucuronosyltransferase in the brainNeuropharmacology, 1987
- Existence of multiple forms of microsomal epoxide hydrolases with radically different substrate specificitiesCarcinogenesis: Integrative Cancer Research, 1984
- Isolation of metabolically active capillaries from rat brain1,2Journal of Neurochemistry, 1975
- ENZYMES OF THE γ‐GLUTAMYL CYCLE IN THE CHOROID PLEXUS AND BRAINJournal of Neurochemistry, 1974