Differential Effects of Naturally Occurring Isothiocyanates on the Activities of Cytochrome P450 2E1 and the Mutant P450 2E1 T303A

This publication has 24 references indexed in Scilit:

• Inactivation of Cytochrome P450 2E1 by Benzyl Isothiocyanate
  Chemical Research in Toxicology, 1999
• Inhibition of rat liver cytochrome P450 isozymes by isothiocyanates and their conjugates: a structure-activity relationship study
  Carcinogenesis: Integrative Cancer Research, 1996
• Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by human cytochrome P450 1A2 and its inhibition by phenethyl isothiocyanate
  Carcinogenesis: Integrative Cancer Research, 1996
• Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes
  Carcinogenesis: Integrative Cancer Research, 1992
• A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure.
  Proceedings of the National Academy of Sciences, 1992
• Crystal structure of the cytochrome P-450CAM active site mutant Thr252Ala
  Biochemistry, 1991
• Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects
  Chemical Research in Toxicology, 1991
• Uncoupling of the cytochrome P-450cam monooxygenase reaction by a single mutation, threonine-252 to alanine or valine: possible role of the hydroxy amino acid in oxygen activation.
  Proceedings of the National Academy of Sciences, 1989
• Inhibitory effects of benzyl isothiocyanate administered shortly before diethylnitrosamine or benzo[a]pyrene on pulmonary and forestomach neoplasia in A/J mice
  Carcinogenesis: Integrative Cancer Research, 1987
• Inhibition of Carcinogenic Effects of Polycyclic Hydrocarbons by Benzyl Isothiocyanate and Related Compounds2
  JNCI Journal of the National Cancer Institute, 1977