A new folate antimetabolite, 5,10-dideaza-5,6,7,8-tetrahydrofolate is a potent inhibitor of de novo purine synthesis
Open Access
- 1 January 1989
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 264 (1) , 328-333
- https://doi.org/10.1016/s0021-9258(17)31261-9
Abstract
No abstract availableThis publication has 20 references indexed in Scilit:
- Inhibition of mannose incorporation into glycoproteins and dolichol-linked intermediates of sarcoma 180 cells by 6-methylmercaptopurine ribonucleosideInternational Journal of Cancer, 1987
- Mammalian folylpoly-.gamma.-glutamate synthetase. 3. Specificity for folate analogsBiochemistry, 1987
- Synthesis of the antileukemic agents 5,10-dideazaaminopterin and 5,10-dideaza-5,6,7,8-tetrahydroaminopterinJournal of Medicinal Chemistry, 1985
- Mammalian folyl polyglutamate synthetase: partial purification and properties of the mouse liver enzymeBiochemistry, 1984
- l(-)-10-Formyltetrahydrofolate is the cofactor for glycinamide ribonucleotide transformylase from chicken liverBiochemistry, 1981
- A potent antitumour quinazoline inhibitor of thymidylate synthetase: Synthesis, biological properties and therapeutic results in micePublished by Elsevier ,1981
- Methotrexate di-n-butyl ester effects on thymidine metabolismBiochemical Pharmacology, 1979
- Cell-Cycle Analysis in 20 MinutesScience, 1974
- Tetrahydrohomofolate, a Specific Inhibitor of Thymidylate SynthetaseJournal of the American Chemical Society, 1964
- Temporary Remissions in Acute Leukemia in Children Produced by Folic Acid Antagonist, 4-Aminopteroyl-Glutamic Acid (Aminopterin)New England Journal of Medicine, 1948