Primary structure of α-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence
- 1 October 1982
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 299 (5886) , 793-797
- https://doi.org/10.1038/299793a0
Abstract
DNA sequences complementary to the Torpedo californica electroplax mRNA coding for the α-subunit precursor of the acetylcholine receptor were cloned. The nucleotide sequence of the cloned cDNA indicates that the precursor consists of 461 amino acids including a prepeptide of 24 amino acids. Possible sites for acetylcholine binding and antigenic determinants on the α-subunit molecule are discussed.Keywords
This publication has 44 references indexed in Scilit:
- Acetylcholine Receptor: Complex of Homologous SubunitsScience, 1980
- Biochemical properties of acetylcholine receptor subunits from Torpedo californicaBiochemistry, 1979
- Studies of the composition of purified Torpedo californica acetylcholine receptor and of its subunitsBiochemistry, 1979
- Comparison of the subunits of Torpedo californica acetylcholine receptor by peptide mappingBiochemistry, 1979
- Structural and Functional Properties of the Acetylcholine Receptor Protein in its Purified and Membrane-Bound StatesAnnual Review of Biochemistry, 1978
- Molecular weight in detergent solution of acetylcholine receptor from Torpedo californicaBiochemistry, 1978
- The Acetylcholine Receptor as Part of a Protein Complex in Receptor-Enriched Membrane Fragments from Torpedo californica Electric TissueEuropean Journal of Biochemistry, 1978
- Facets of the Structures of Acetylcholine Receptors from Electrophorus and TorpedoCold Spring Harbor Symposia on Quantitative Biology, 1976
- Characterization of Torpedo californica Acetylcholine Receptor: Its Subunit Composition and Ligand-binding PropertiesCold Spring Harbor Symposia on Quantitative Biology, 1976
- Affinity-labeling of purified acetylcholine receptor from Torpedo californicaBiochemical and Biophysical Research Communications, 1974