Abstract
The fingertip skin ridge patterns of 10 children with the congenital rubella syndrome whose mothers had received .gamma.-globulin following exposure to german measles during pregnancy were compared with those of 29 patients whose mothers had not received .gamma.-globulin and with those of 162 control children. Statistical evaluation of the pattern profiles by the Mann-Whitney U-test showed that the dermatoglyphics of the 2 groups of patients differed significantly from each other. Each group differed from the control children: there was a significant (P < 0.001) increase in whorls in patients whose mothers had not had .gamma.-globulin, but an increase (P = 0.001) in ulnar loops in those whose mothers had received .gamma.-globulin.