Characterization of an imidazolium compound formed by reaction of methylglyoxal and Nα-hippuryllysine
- 1 January 1995
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 22,p. 2817-2818
- https://doi.org/10.1039/p19950002817
Abstract
The 1,3-di-Nα-hippuryllysino-4-methylimidazolium salt 6 has been identified as a major product of reaction of the α-dicarbonyl compound, methylglyoxal 1, with the lysine derivative, Nα-hippuryllysine (Nα-benzoylglycyllysine)2, in phosphate buffer at neutral pH, suggesting a mechanism for crosslinking of protein by 1 and related dicarbonyl compounds during the Maillard reaction.Keywords
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