Deprotection of Acetals and Ketals by Silica Sulfuric Acid and Wet SiO2
Open Access
- 30 October 2002
- Vol. 7 (10) , 751-755
- https://doi.org/10.3390/71000751
Abstract
Neat chlorosulfonic acid reacts with silica gel to give silica sulfuric acid in which sulfuric acid is immobilized on the surface of silica gel via covalent bonds. A combination of silica sulfuric acid and wet SiO2 was used as an effective deacetalizating agent for the conversion of acetals to their corresponding carbonyl derivatives under thermal conditions.Keywords
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