Could Aspirin Really Prevent Colon Cancer?

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Abstract
IN the United States, tumors of the colon and rectum account for approximately 15 percent of all visceral cancers and about 12 percent of all deaths from cancer. During the past several decades, the incidence of these cancers has remained relatively constant, and the associated mortality has declined only slightly, despite intensive attempts at earlier detection and better treatment. Research into ways to lessen the incidence or mortality has yielded only equivocal results. In several large ongoing studies conducted for up to 12 years, no clear reduction in mortality has resulted from screening for occult blood in feces.1 Among the . . .